What Is Sleep Quality? | National Sleep Foundation | Health Updates

What Is Sleep Quality?

What Is Sleep Quality?

As people pay more and more attention to the serious side effects of prescription and over-the-counter sleeping pills, What Is Sleep Quality?  it is very important for consumers to seek safe and effective natural products that help improve sleep quality.

A new study conducted on the natural form of GABA (PharmaGABA) shows that the product is more effective in helping sleep at night.

Background data:

Gamma-aminobutyric acid (GABA) is a major neurotransmitter widely distributed in the central nervous system (CNS). Decreased content or decreased effect of this component (GABA (Gamma-Aminobutyric Acid)) is related to a variety of mental diseases and neurological diseases, mainly anxiety, depression, insomnia, and epilepsy.

The natural GABA (gamma-aminobutyric acid) produced by the fermentation process of Lactobacillus hillside has shown an effect that cannot be achieved by the synthetic form of GABA (gamma-aminobutyric acid). The synthetic form of GABA (gamma-Aminobutyric acid) is produced from pyrrolidinone-an industrial solvent. The following data can prove that this natural form of PharmaGABA can produce a relaxing effect:

  • Increase the α/β brain wave ratio.
  • Maintain the production of antibodies in saliva during the stress response.
  • Reduce signs of stress, including cortisol levels.

Once ingested, it exhibits an easily absorbed effect and binds to GABA (gamma-aminobutyric acid) receptors in the peripheral nervous system, and then activates the parasympathetic nervous system. This branch of the autonomic nervous system is mainly used to produce a “relaxation response”-this response is a physiological response that is directly opposed to a stress response or a “fight or flight” response. The priming effect of PharmaGABA on the parasympathetic nervous system can be detected within 5 to 30 minutes after ingestion.

The latest data:

In order to evaluate the efficacy of PharmaGABA in improving sleep, a placebo-controlled study was conducted to measure brain waves by electroencephalography after subjects took 100 mg of PharmaGABA or a placebo. The results of the study show that PharmaGABA (gamma-aminobutyric acid) can effectively shorten the time to sleep to 5 minutes, and can improve high-quality sleep time compared to the placebo control group. The questionnaire showed that the sleep quality of the subjects taking PharmaGABA improved, especially the energy after waking up.

The positive drug effect can be explained by the following mechanisms, including PharmaGABA’s sleep-improving effect may be related to its ability to stimulate the parasympathetic nervous system and stress relief. An early study showed that it can activate the parasympathetic nervous system to lower the body’s core body temperature, which can promote sleep.

The study also measured the concentration of GABA (gamma-aminobutyric acid) in the blood after taking PharmaGABA. The results show that GABA (Gamma-Aminobutyric Acid) has been rapidly absorbed, and the maximum concentration of GABA (Gamma-Aminobutyric Acid) in the blood appears 30 minutes after oral administration. Researchers believe that taking GABA (Gamma-Aminobutyric Acid) 30 minutes before going to bed has the best effect on promoting sleep.


PharmaGABA can be used to improve the quality of sleep, and it can also be used when the body feels “tension”. Under stress, you can take 100 to 200 mg three times a day. To promote better night sleep quality, 100 to 200 mg can be taken before going to bed. PharmaGABA is absolutely safe and has no known adverse reactions. As a general medication guide, it is recommended that the dosage within 6 hours does not exceed 600 mg, and the dosage within 24 hours does not exceed 1200 mg.

The main reason that GABA (Gamma-Aminobutyric Acid) can achieve this effect is the use of natural forms of GABA (Gamma-Aminobutyric Acid), such as PharmaGABA, which is produced by the fermentation process. The synthetic form ingredients produced from chemical solvents did not show the same medicinal effects.


  • Yamato A, Yamashita Y, Pandharipande T, Maru I, Kim M. Effect of Oral γ-aminobutyric Acid (GABA) Administration on Sleep and its Absorption in Humans. Food Sci. Biotechnol. 2016:25(2): 547-551.

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